Kiefer Sutherland – Jack Bauer | Carlos Bernard – Tony Almeida | Mary Lynn Rajskub – Chloe O’Brian | Dennis Haysbert – David Palmer | Elisha Cuthbert – Kim Bauer | James Morrison – Bill Buchanan | Reiko Aylesworth – Michelle Dessler | Kim Raver – Audrey Raines | D.B. Woodside – Wayne Palmer
Jacob Hood – Rufus Sewell | Rachel Young – Marley Shelton | Felix Lee – Omar Benson Miller
Milo Ventimiglia – Peter Petrelli | Santiago Cabrera – Isaac Mendez | Masi Oka – Hiro Nakamura | Greg Grunberg – Matt Parkman | Hayden Panettiere – Claire Bennet | Adrian Pasdar – Nathan Petrelli | Ali Larter – Niki Sanders | Leonard Roberts – D. L. Hawkins | Zachary Quinto – Sylar | Jack Coleman – Noah Bennet
Matthew Fox – Jack Shephard | Evangeline Lilly – Kate Austen | Josh Holloway – James “Sawyer” Ford | Terry O’Quinn – John Locke | Naveen Andrews – Sayid Jarrah | Jorge Garcia – Hugo “Hurley” Reyes | Dominic Monaghan – Charlie Pace | Emilie de Ravin – Claire Littleton | Yoon-jin Kim – Sun Kwon | Daniel Dae Kim – Jin-Soo Kwon | Harold Perrineau Jr. – Michael Dawson | Malcolm David Kelley – Walt Lloyd | Ian Somerhalder – Boone Carlyle | Maggie Grace – Shannon Rutherford | Michelle Rodríguez – Ana-Lucía Cortez | Adewale Akinnuoye-Agbaje – Mr. Eko | Henry Ian Cusick – Desmond David Hume | Michael Emerson – Benjamin Linus
Anna Torv – Olivia Dunham | John Noble – Walter Bishop | Joshua Jackson – Peter Bishop | Lance Reddick – Phillip Broyles | Kirk Acevedo – Charlie Francis | Blair Brown – Nina Sharp
Joseph Fiennes – Mark Benford | John Cho – Demetri Noh | Jack Davenport – Lloyd Simcoe | Zachary Knighton – Bryce Varley | Dominic Monaghan – Simon Campos | Peyton List – Nicole Kirby | Brían F. O’Byrne – Aaron Stark
Enrico Colantoni – Srż. Gregory Parker | Hugh Dillon – Ed Lane | Ona Grauer – Kate Travers | Gabriel Hogan – Roland Cray | Michael Cram – Kevin ‘Wordy’ Wordsworth | Sergio Di Zio – Michaelangelo ‘Spike’ Scarlatti | Adam Brazier – Steve ‘Shakes’ Bonnyman | David Paetkau – Sam Braddock | Amy Jo Johnson – Julianna ‘Jules’ Callaghan
